Background: the identification of human skin through mRNA-based profiling is useful in forensic investigations. A deliberate attempt to remove biological material, through using a variety of cleaning agents, is a problem faced by forensic scientists. Limited information exists on the effect of Hypochlorite (HOCl); cleaning agent; on human skin mRNA markers. Aim: This study evaluated the sensitivity of specific human genetic skin markers; LCE2D and CCL27 to different HOCl concentrations by using Real-time qPCR. Method: sixty four middle aged healthy volunteers (32 males and 32 females) were included in the study.Results: HOCl had a pronounced negative effect. The expression of the studied markers was decreased to the quarter of its normal value when the touch samples were submerged in concentrated HOCl solution. Conclusion: sample with reduced RNA expressions might be soaked or adulterated before testing and other tests should be used to help in cellular origin determination
(2018). THE EFFECT OF HYPOCHLORITE ON SKIN'S MRNA MARKERS IN CONTACT SAMPLES. The Egyptian Journal of Forensic Sciences and Applied Toxicology, 18(1), 55-61. doi: 10.21608/ejfsat.2018.28294
MLA
. "THE EFFECT OF HYPOCHLORITE ON SKIN'S MRNA MARKERS IN CONTACT SAMPLES". The Egyptian Journal of Forensic Sciences and Applied Toxicology, 18, 1, 2018, 55-61. doi: 10.21608/ejfsat.2018.28294
HARVARD
(2018). 'THE EFFECT OF HYPOCHLORITE ON SKIN'S MRNA MARKERS IN CONTACT SAMPLES', The Egyptian Journal of Forensic Sciences and Applied Toxicology, 18(1), pp. 55-61. doi: 10.21608/ejfsat.2018.28294
VANCOUVER
THE EFFECT OF HYPOCHLORITE ON SKIN'S MRNA MARKERS IN CONTACT SAMPLES. The Egyptian Journal of Forensic Sciences and Applied Toxicology, 2018; 18(1): 55-61. doi: 10.21608/ejfsat.2018.28294
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